The following is the full transcript of an interview with NASA Administrator Jared Isaacman that aired on "Face the Nation with Margaret Brennan" on April 5, 2026.

The Artemis II crew provides an inspiring message from space, now closer to the Moon than Earth, capturing unique perspectives of our planet. NASA engineers also addressed a minor plumbing issue in the Orion spacecraft and continue testing new custom-fit orange space suits for crew safety.

NASA has launched a Q&A page for its Artemis II mission as astronauts prepare for a six-hour lunar flyby Monday.

The Artemis II crew is nearing the Moon on a historic flyby mission, sending back new images as NASA moves closer to landing humans there again by 2028.

The Artemis 2 mission is due to send astronauts on a test mission to the moon and back during the "opening act" of a new age of discovery.

NASA released new lunar photos as Artemis II astronauts pass the halfway point in their moonbound journey.

NASA's Imaging X-ray Polarimetry Explorer reveals the expansion and shock patterns within RCW 86, a supernova observed by early astronomers in A.D. 185.

The astronauts and cameras on NASA's Artemis II mission are capturing stunning photos of the Earth, moon and Orion spacecraft.

NASA Administrator Jared Isaacman says answering the question of alien life is inherent in all space exploration, and the odds of finding evidence at some point that suggests we’re not alone is “pretty high.